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KMID : 0358819830100010119
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Journal of Korean Society of Plastic and Reconstructive Surgeons
1983 Volume.10 No. 1 p.119 ~ p.124
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HISTOLOGIC ALTERATIONS IN SEVERELY BURNED RAT SKIN
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Cho Hyun-Chol
Choi Kyu-Nam
Choi Hee-Youn
Kim Han-Jung
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Abstract
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One of the persistent problems plaguing surgeons who treat burn victims is the difficulty in quickly assessing the depth of burn injury. Often areas of second-and third-degree burns are intermingled and difficult to accurately evaluate soon after injury.
The lag phase between time of injury and development of morphologic evidence of damage is reported to be at lease 8 hours. with full development of damage becoming evident by 24 hours to 2 days after burning. A method to detect and document early manifestations of burn injury is needed.
In this study, fifteen male Wister Albino rats weighing 200 to 300gm were used as experimental subjects, and the goal of this study is to define clearly the early morphologic events following a severe burn.
In conclusion, histologic alteration was used in this study as a tool for diagnosis of the depth of a burn injury. It was proved useful method in making early diagnosis of burn injury, and it was also revealed the fact which burn injury is a progressive phenomenon.
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KEYWORD
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